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Dentist

Swinburne stem-cell technology aids 3D printed cartilage repair

Novel stem-cell technology developed at Swinburne will be used to grow the massive number of stem cells required for a new hand-held 3D printer that will enable surgeons to create patient-specific bone and cartilage. The technology, called BioSphere, is being developed in collaboration with St Vincent’s Hospital in Melbourne to support the development of Biopen. […]

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Dentist

New light shed on how bone marrow niches keep stem cells thriving

Japanese researchers uncover cellular factor needed to maintain the environment that regulates hematopoietic stem cell Osaka – Hematopoietic stem cells (HSCs) are a class of stem cells located in bone marrow. HSCs give rise to every type of blood cell–from the red blood cells that carry oxygen to the white blood cells of the immune […]

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Dentist

Bioengineered tooth bud model functionalized with decellularized tooth bud ECM

Alexandria, VA, USA – At the 47th Annual Meeting of the American Association for Dental Research (AADR), held in conjunction with the 42nd Annual Meeting of the Canadian Association for Dental Research (CADR), Alen Blagajcevic, student at Tufts University School of Dental Medicine, Boston, Mass., presented an oral session titled “Bioengineered Tooth Bud Model Functionalized […]

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Dentist

Transplantation of Hepatocyte Growth Factor–Modified Dental Pulp Stem Cells Prevents Bone Loss in the Early Phase of Ovariectomy-Induced Osteoporosis

Abstract Investigations based on mesenchymal stem cells (MSCs) for osteoporosis have attracted attention recently. MSCs can be derived from various tissues, such as bone marrow, adipose, umbilical cord, placenta, and dental pulp. Among these, dental pulp–derived MSCs (DPSCs) and hepatocyte growth factor (HGF)-modified DPSCs (DPSCs-HGF) highly express osteogenic-related genes and have stronger osteogenic differentiation capacities. […]

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Dentist

Nikon enters into a business alliance to establish a clinical-use master cell bank, to be utilized for regenerative medicine products derived from dental pulp cells for the first time in Japan.

Nikon Corporation (Kazuo Ushida, President, Tokyo) has announced a business alliance agreement (hereinafter referred to as the “agreement”) with Advanced Cell Technology and Engineering Ltd. (Koichi Otomo, President, Tokyo, hereinafter referred to as “ACTE”) in order to establish a clinical-use master cell bank (MCB)*1, to be employed for regenerative medicine products derived from dental pulp […]

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Dentist

The phenotype, psychotype and genotype of bruxism

Authors: Norma Cruz‑Fierro Margarita Martínez‑Fierro Ricardo M. Cerda‑Flores Mayra A. Gómez‑Govea Iván Delgado‑Enciso Laura E. Martínez‑De‑Villarreal Mónica T. González‑Ramírez Irám Pablo Rodríguez‑Sánchez View Affiliations Published online on: January 15, 2018 https://doi.org/10.3892/br.2018.1041 Pages:264-268 Abstract Bruxism is a jaw muscle activity that involves physio-pathological, psycho‑social, hereditary and genetic factors. The purpose of this study was to determine […]

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Dentist

Periodontal Regeneration Using Dental Pulp Stem Cells (DPSCs)

Experimental: Dental pulp stem cells Test sites (n=15) Periodontal regeneration using micro-grafts of Dental pulp stem cells seeded onto collagen sponge Procedure: periodontal regeneration Defects were accessed with the MIST In the test group the obtained micro-grafts enriched in DPSCs were endorsed onto a collagen sponge scaffold (Condress®, Istituto Gentili, Milano, Italy) to form a […]

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Dentist

Can Tooth Decay Explain the Pathogenesis of Certain Infectious Diseases?

Infectious disease specialists looking for breakthrough findings have something to, well, sink their teeth into. A review published October 30, 2017, in the journal Trends in Microbiology, highlights the importance of biofilms in improved understanding of the “local microenvironment where pathogens and commensals interact.” As the authors, from the Division of Community Oral Health at […]

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Dentist

Sex determination of human remains from peptides in tooth enamel

The assignment of biological sex to archaeological human skeletons is a fundamental requirement for the reconstruction of the human past. It is conventionally and routinely performed on adults using metric analysis and morphological traits arising from postpubertal sexual dimorphism. A maximum accuracy of ∼95% is possible if both the cranium and os coxae are present […]

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Dentist

Cells spun from baby teeth implicate astrocytes in autism

Star-shaped brain cells from children with autism release inflammatory molecules that harm neurons, a new study suggests1. Researchers derived the cells, called astrocytes, from the children’s teeth, and cultured them alongside neurons. The new work hints that blocking inflammatory molecules from astrocytes could protect neurons in people with autism. “There’s a chance that we could […]

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Dentist

Exfoliated Deciduous Tooth as the Source of Stem Cells: A Technique for Proliferation and Chromosome Analysis In Vitro

Abstract: Since a long time, the field of stem cell biology has undergone a remarkable transformation with constant research on it and its various applications predicated to be coming into use for long term clinical cell based therapies. The present report describes extraction of mesenchymal cells from deciduous tooth and its propagation in vitro with […]

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Dentist

Dentists Find Tooth Root Pulp Can Become an Alternative Source of Stem Cells

WISDOM IN TEETH A collaboration of dentists and engineers from the University of Nevada, Las Vegas (UNLV) made a discovery that could potentially revolutionize how and where we harvest, preserve, and use stem cells. In a study published in Biomaterials and Biomechanics in Bioengineering, the team led by UNLV biomedical sciences professor Karl Kingsley and […]

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Dentist

Does brain tissue regeneration depend on maturity of stem cells used for transplantation?

New research has shown that the success of transplanting stem cells into the brain to regenerate tissue damaged by stroke may depend on the maturity of the neuronal precursor cells used for transplantation. A study demonstrating the significant impact of human neuronal precursor cell maturity on cell survival after transplantation into stroke-injured rate brains is […]

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