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Dentist

Nikon enters into a business alliance to establish a clinical-use master cell bank, to be utilized for regenerative medicine products derived from dental pulp cells for the first time in Japan.

Nikon Corporation (Kazuo Ushida, President, Tokyo) has announced a business alliance agreement (hereinafter referred to as the “agreement”) with Advanced Cell Technology and Engineering Ltd. (Koichi Otomo, President, Tokyo, hereinafter referred to as “ACTE”) in order to establish a clinical-use master cell bank (MCB)*1, to be employed for regenerative medicine products derived from dental pulp […]

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Dentist

The End Of Root Canals: Stem Cell Fillings Trigger Teeth To Repair Themselves, Research Study Claims

What if damaged teeth could heal themselves without the need of a root canal? Apparently, that’s what Harvard and the University of Nottingham are trying to figure out. They believe they can create stem cell stimulated fillings. Worldwide, dentists treat hundreds of millions of cavities each year by drilling out the decayed part of the […]

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Dentist

Periodontal Regeneration Using Dental Pulp Stem Cells (DPSCs)

Experimental: Dental pulp stem cells Test sites (n=15) Periodontal regeneration using micro-grafts of Dental pulp stem cells seeded onto collagen sponge Procedure: periodontal regeneration Defects were accessed with the MIST In the test group the obtained micro-grafts enriched in DPSCs were endorsed onto a collagen sponge scaffold (Condress®, Istituto Gentili, Milano, Italy) to form a […]

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Dentist

Synthetic Light-Curable Polymeric Materials Provide a Supportive Niche for Dental Pulp Stem Cells

Dental disease annually affects billions of patients, and while regenerative dentistry aims to heal dental tissue after injury, existing polymeric restorative materials, or fillings, do not directly participate in the healing process in a bioinstructive manner. There is a need for restorative materials that can support native functions of dental pulp stem cells (DPSCs), which […]

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Dentist

Exfoliated Deciduous Tooth as the Source of Stem Cells: A Technique for Proliferation and Chromosome Analysis In Vitro

Abstract: Since a long time, the field of stem cell biology has undergone a remarkable transformation with constant research on it and its various applications predicated to be coming into use for long term clinical cell based therapies. The present report describes extraction of mesenchymal cells from deciduous tooth and its propagation in vitro with […]

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Dentist

Scientists Have Discovered a Drug That Fixes Cavities and Regrows Teeth

Dental fillings may soon be left in the ash heap of history, thanks to a recent discovery about a drug called Tideglusib. Developed for and trialled to treat Alzheimer’s disease, the drug also happens to promote the natural tooth regrowth mechanism, allowing the tooth to repair cavities. Tideglusib works by stimulating stem cells in the […]

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Dentist

Dentists Find Tooth Root Pulp Can Become an Alternative Source of Stem Cells

WISDOM IN TEETH A collaboration of dentists and engineers from the University of Nevada, Las Vegas (UNLV) made a discovery that could potentially revolutionize how and where we harvest, preserve, and use stem cells. In a study published in Biomaterials and Biomechanics in Bioengineering, the team led by UNLV biomedical sciences professor Karl Kingsley and […]

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Dentist

Solutions: Saving Decayed Teeth with Stem Cells

A dentist is researching alternatives to root canal treatment and extraction Ariadne Letra, D.D.S., Ph.D., director of research in the department of endodontics at UTHealth’s School of Dentistry, and Renato Silva, D.D.S., Ph.D., associate professor and chair of the department of endodontics at UTHealth, demonstrate how their team analyzes samples. By Christine Hall | October […]

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Dentist

Scientists Have Developed Stem Cell Fillings That Help Your Teeth Heal Themselves

Using a regenerative approach researchers from both Harvard University and the University of Nottingham found a way to teach one part of our body to heal itself. By  Danielle De La Bastide Scientists from the Universities of Nottingham and Harvard may have come up with a way to teach our teeth to heal themselves without […]

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Dentist

Researchers compare effectiveness of natural and synthetic materials for dental pulp tissue engineering

To regenerate dental pulp tissue after emptying of a tooth’s root canals researchers compared the effectiveness of 3D scaffolds made of natural or customized synthetic materials containing pulpal stem cells and dentin-derived growth factors. The substantial differences in terms of scaffold degradation, cell viability, vascularization, and pulpal tissue formation are reported in Tissue Engineering, Part […]

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Dentist

Oxidative stress in patients with endodontic pathologies

Veiko Vengerfeldt,1 Reet Mändar,2,3 Mare Saag,1 Anneli Piir,2 Tiiu Kullisaar2 1Institute of Dental Sciences, Faculty of Medicine, University of Tartu, 2Institute of Biomedicine and Translational Medicine, Faculty of Medicine, University of Tartu, 3Competence Centre on Health Technologies, Tartu, Estonia Background: Apical periodontitis (AP) is an inflammatory disease affecting periradicular tissues. It is a widespread condition […]

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Dentist

Selecting most effective materials for dental pulp tissue engineering

To regenerate dental pulp tissue after emptying of a tooth’s root canals researchers compared the effectiveness of 3D scaffolds made of natural or customized synthetic materials containing pulpal stem cells and dentin-derived growth factors. The substantial differences in terms of scaffold degradation, cell viability, vascularization, and pulpal tissue formation are reported in Tissue Engineering, Part […]

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